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Scientific Poster Orbitrap Exploris 480 Bottom-up Proteomics

Reliable and Deep Proteome Coverage by Gas-Phase Fractionation of Peptides with a FAIMS Pro Interface on a Modified Quadrupole Orbitrap

Julia Kraegenbring1, Tabiwang N. Arrey1, Michael W. Belford2, Satendra Prasad2, Kerstin Strupat1, Markus Kellmann1, Thomas Moehring1, and Alexander Harder1

Hupo 2019

1 Thermo Fisher Scientific, 28199 Bremen, Germany 2 Thermo Fisher Scientific, San Jose, CA 95134


Purpose: Demonstrate the benefit of Thermo Scientific™ FAIMS Pro™ interface for proteomic data-dependent experiments and establish an optimized method setup with the new Thermo Scientific™ Orbitrap Exploris™ 480 mass spectrometer.

Methods: A commercially available tryptic HeLa…

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