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Scientific Paper Any Orbitrap PPCC - Cross Linking

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study

Claudio Iacobucci,a,# Christine Piotrowski,a,# Ruedi Aebersold,b,c Bruno C. Amaral,d Philip Andrews,e Katja Bernfur,q Christoph Borchers,f,g,h,i Nicolas I. Brodie,f James E. Bruce,j Yong Cao,o Stephane Chaignepain, ́ k Juan D. Chavez,j Stephane Claverol, ́ l Jürgen Cox,m Trisha Davis,oo Gianluca Degliesposti,n Meng-Qiu Dong,o Nufar Edinger,p Cecilia Emanuelsson,q Marina Gay,r Michael Götze,s Francisco Gomes-Neto,rr Fabio C. Gozzo,d Craig Gutierrez,t Caroline Haupt,u Albert J. R. Heck,v Franz Herzog,w Lan Huang,t Michael R. Hoopmann,x Nir Kalisman,p Oleg Klykov,v Zdenek Kukac ̌ ka, ̌ y Fan Liu,z Michael J. MacCoss,aa Karl Mechtler,bb Ravit Mesika,p Robert L. Moritz,x Nagarjuna Nagaraj,cc Victor Nesati,dd Ana G. C. Neves-Ferreira,rr Robert Ninnis,dd Petr Novak, ́ y Francis J. O’Reilly,ee Matthias Pelzing,dd Evgeniy Petrotchenko,f Lolita Piersimoni,e Manolo Plasencia,e Tara Pukala,ff Kasper D. Rand,gg Juri Rappsilber,ee,hh Dana Reichmann,p Carolin Sailer,ii Chris P. Sarnowski,b,jj Richard A. Scheltema,v Carla Schmidt,u David C. Schriemer,kk Yi Shi,nn J. Mark Skehel,n Moriya Slavin,p Frank Sobott,pp,qq Victor Solis-Mezarino,w Heike Stephanowitz,z Florian Stengel,ii Christian E. Stieger,bb Esben Trabjerg,gg Michael Trnka,ll Marta Vilaseca,r Rosa Viner,mm Yufei Xiang,nn Sule Yilmaz,m Alex Zelter,oo Daniel Ziemianowicz,kk Alexander Leitner,*,b and Andrea Sinz*,a

Anal. Chem. 2019, 91, 6953−6961


The number of publications in the field of chemical cross-linking combined with mass spectrometry (XL-MS) to derive constraints for protein three-dimensional structure modeling and to probe protein–protein interactions has increased during the last years. As the technique is now…

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