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Scientific Poster Q Exactive Plus Bottom-up Proteomics

Proteomic Analysis of Cell Surface Proteins with Improved Specificity of Enrichment

Betsy Benton, Sergei Snovida, Katherine Herting, Hongbin Zhu, John C. Rogers, and Barbara Kaboord

ASMS 2019 Poster

Thermo Fisher Scientific, 3747 North Meridian Rd., Rockford, IL, 61101

Purpose: Enrichment of cell surface proteins is commonly performed by biotinylation using amine-based chemistry; however, this method is often associated with intracellular labeling and difficulty distinguishing the true cell surface proteins from background contaminants. Here, we have…

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