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Technical Guide Orbitrap Fusion Lumos, Orbitrap Fusion, Q Exactive HF, Q Exactive HF-X, Q Exactive, Q Exactive Plus RQ - TMT

A quality control standard for tandem mass tags (tmt) proteomic workflows

Aaron M. Robitaille1, Jae Choi2, Rosa Viner1, Andreas Huhmer1, Kay Opperman2, John C. Rogers2

TECHNICAL NOTE 72968

1 Thermo Fisher Scientific, 355 River Oaks Pkwy, San Jose, CA 95134. 2 Thermo Fisher Scientific, 3747 N Meridian Rd, Rockford, IL 61101.


Quantitative proteomics strategies using Tandem Mass Tag™ (TMT™) reagents enable sample multiplexing and precise measurement of protein abundance. However, successful execution of this workflow includes multiple steps that may require optimization including liquid chromatography (LC),…

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