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Scientific Paper Orbitrap Fusion Lumos RQ - TMT, Targeted Quantitation

TomahaqCompanion: A tool for the creation and analysis of isobaric label based multiplexed targeted assays

Christopher M. Rose1, Brian K. Erickson2 , Devin K. Schweppe2 , Rosa Viner3 , Jae Choi4 , John Rogers4 , Ryan Bomgarden4 , Steven P. Gygi2 , Donald S. Kirkpatrick

J Proteome Res. 2018 Dec 3. doi: 10.1021/acs.jproteome.8b00767

1. Department of Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, CA 94080, United States. 2. Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States. 3. Thermo Fisher Scientific, San Jose, CA 95134, United States 4. Thermo Fisher Scientific, Rockford, Illinois 61101, United States


Triggered by Offset, Multiplexed, Accurate mass, High resolution, and Absolute Quantitation (TOMAHAQ) is a recently introduced targeted proteomics method that combines peptide and sample multiplexing. TOMAHAQ assays enable sensitive and accurate multiplexed quantification by implementing…

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