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Scientific Poster Orbitrap Fusion Lumos PROTEINS - ALL

Enrichment Strategies for Improving Mass Spec Analysis of Chemically Crosslinked Peptides

1Rosa Viner, 2Ryan Bomgarden, 2Kratika Singhal, 2Sergei Snovida, 3Craig Gutierrez, 3Lan Huang

ASMS 2017 Poster

1 Thermo Fisher Scientific, San Jose, CA 2 Thermo Fisher Scientific, Rockford, IL 3 University of California, Irvine, Irvine, CA


Purpose: To evaluate multiple, widely used enrichment/fractionation techniques and benchmark newly developed strong cation exchange (SCX) spin columns for cross-linked peptide analysis using a Thermo Scientific™ Orbitrap Fusion™ Lumos™ Tribrid™ mass spectrometer.

Methods:…

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