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Application Note Orbitrap Fusion, Q Exactive Plus Post-Translational Modification Analysis, PTM - Phosphorylation, PTM - Other

Optimized Search Strategy to Maximize PTM Characterization and Protein Coverage in Proteome Discoverer Software

Xiaoyue Jiang1, David Horn1, Michael Blank1, Devin Drew1, Bernard Delanghe2, Rosa Viner1, Andreas FR Huhmer1

Application Note 658

1Thermo Fisher Scientific, San Jose, CA, USA; 2Thermo Fisher Scientific, Bremen, Germany

To evaluate several commonly used search algorithms to maximize peptide/protein identifications and PTM signatures for different types of samples.

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