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Scientific Poster Q Exactive HF Untargeted Metabolomics

High-throughput Targeted Metabolomic Analysis in Oral Cancer Cells using Automated Column Switching and Ion Chromatography Coupling to a HR/AM Mass Spectrometer

Terri T. Christison1, Anas Kamleh2; Shen Hu3; Ryo Komatsuzaki1, Ralf Tautenhahn1, Linda Lopez1

1. Sunnyvale-San Jose, USA 2. H├Ągersten, SE 3. Dentistry and Jonsson Comprehensive Cancer Center, UCLA, USA

Purpose: Demonstrate 9-min targeted analysis by IC-HRAM using automated column switching.

Methods: Polar metabolites were determined using ion chromatography coupled with high resolution accurate mass spectrometry (IC_HRAM) facilitated by column switching using the dual IC system…

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