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Scientific Poster RQ - Label-Free

New Method for Label-Free Quantification in the Proteome Discoverer Framework

David M Horn,1 Torsten Ueckert,2 Kai Fritzemeier,2 Katja Tham,2 Carmen Paschke,2 Frank Berg,2 Hans Pfaff,2 Xiaoyue Jiang,1 Shijun Li,1 and Dani Lopez-Ferrer

1Thermo Fisher Scientific, San Jose, CA, USA 2Thermo Fisher Scientific, Bremen, Germany

A new label-free quantification method based on the Minora algorithm is presented and compared to pre-existing label free quantification methods in the Thermo Scientific™ Proteome Discoverer™ software framework. The results of the new algorithm were significantly more accurate across…

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