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Scientific Poster Q Exactive HF-X SureQuant Quantitation

Targeted proteomic characterization of the AKT/mTOR pathway through analysis of clinically derived samples

Rowan Matney1, Kratika Singhal1, Fang Liu1, Sarah Trusiak2, Emily Chen2, Ryan D. Leib1, Allis S. Chien1

International Hupo 2020

1. Stanford University Mass Spectrometry, Stanford, CA 2. Thermo Fisher Precision Medicine Science Center, Cambridge, MA

To tackle questions of differential protein expression in the expanding phosphoproteome, one emerging strategy is the targeted measurement of protein candidates from critical pathways. Here, we use a targeted sample preparation strategy (SureQuant) to enrich clinical tissue samples for…

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