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Scientific Poster Orbitrap Eclipse, Orbitrap Exploris 480 SureQuant Quantitation

Optimized Informatic Pipeline for the Automated Execution of SureQuant Workflow on Orbitrap Mass Spectrometers

Sebastien Gallien1,2, Aaron S. Gajadhar3, Bhavin Patel4, Carmen Paschke5, Dave Horn3, Nicholas Shulman6, Bernard Delanghe5, Brendan MacLean6, Daniel Lopez-Ferrer3, Emily I. Chen2, Shannon Eliuk3, Andreas Huhmer3

International Hupo 2020

1Thermo Fisher Scientific, Paris, France; 2Thermo Fisher Scientific, Precision Medicine Science Center, Cambridge, MA, USA; 3Thermo Fisher Scientific, San Jose, CA, USA; 4Thermo Fisher Scientific, Rockford, IL, USA; 5Thermo Fisher Scientific, Bremen, Germany; 6University of Washington, Seattle, WA, USA.

The SureQuantTM methodology has recently been implemented natively in the instrument control software of Orbitrap-based mass spectrometers. It uses spiked-in internal standards (IS) to dynamically control the acquisition process and to maximize its productivity. In addition to the…

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