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Scientific Paper Orbitrap Fusion Lumos, Orbitrap Eclipse RQ - TMT

Benchmarking the Orbitrap Tribrid Eclipse for Next Generation Multiplexed Proteomics

Qing Yu1, Joao A Paulo1, Jose Naverrete-Perea1, Graeme C McAlister2, Jesse D Canterbury2, Derek J Bailey2, Aaron M Robitaille2, Romain Huguet2, Vlad Zabrouskov2, Steven P Gygi1, Devin K Schweppe1

Anal. Chem. 2020

1 – Harvard Medical School, Boston, MA 02115 2 – Thermo Fisher Scientific, San Jose, CA 95134


The rise of sample multiplexing in quantitative proteomics for the dissection of complex phenotypic comparisons has been advanced by the development of ever more sensitive and robust instrumentation. Here, we evaluated the utility of the Orbitrap Eclipse Tribrid mass spectrometer…

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