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Scientific Poster Q Exactive HF Targeted Quantitation

Targeted Mass Spectrometry Assay Kits for Absolute Quantitation of Signaling Pathway Proteins

Bhavin Patel1; Penny Jensen1; Leigh Foster1; Renuka Sabnis1; Aaron Gajadhar2; Rosa Viner2; Andreas Huhmer2; Kay Opperman1; John Rogers1

1 Thermo Fisher Scientific, Rockford, IL 2 Thermo Fisher Scientific, San Jose, CA


Purpose: Many genetic mutations in cancer cells alter protein expression from AKT, RAS and TP53 pathways. Quantitative measurements of alterations in the expression of pathway proteins and post-translational modifications (PTM) are necessary for classifying disease states, monitoring…

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