Orbitrap Illustration

Scientific Library

Access peer-reviewed scientific papers, application notes, technical guides, specification sheets, scientific posters, brochures, product support bulletins, webinars, and much more....


Please set up alerts based on your interests for notification of new content added by our scientists.


Remember, you must  register on the site and login to your account to see search results. 

Expand Results
Format
Product
Application
Title
Views
Scientific Paper Orbitrap Fusion, Q Exactive Bottom-up Proteomics, Relative Quantitation, RQ - Label-Free, Untargeted Lipidomics, Untargeted Metabolomics

Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling

Jonathan A Stefely1,2,6, Nicholas W Kwiecien3,4,6, Elyse C Freiberger3,5, Alicia L Richards3,4, Adam Jochem1, Matthew J P Rush3,4, Arne Ulbrich3,4, Kyle P Robinson1,2, Paul D Hutchins3,4, Mike T Veling1,2, Xiao Guo1,4, Zachary A Kemmerer1,2, Kyle J Connors3,4, Edna A Trujillo3,4, Jacob Sokol1,2, Harald Marx3, Michael S Westphall3, Alexander S Hebert3, David J Pagliarini1,2,7 & Joshua J Coon3–5,7

Nat Biotechnol. 2016 Nov;34(11):1191-1197

1. orgridge Institute for Research, Madison, Wisconsin, USA. 2. Department of Biochemistry, University of Wisconsin–Madison, Madison, Wisconsin, USA. 3. Genome Center of Wisconsin, Madison, Wisconsin, USA. 4. Department of Chemistry, University of Wisconsin–Madison, Madison, Wisconsin, USA. 5. Department of Biomolecular Chemistry, University of Wisconsin–Madison, Madison, Wisconsin, USA. 6. These authors contributed equally to this work. 7. These authors jointly supervised this work.


Mitochondrial dysfunction is associated with many human diseases, including cancer and neurodegeneration, that are often linked to proteins and pathways that are not well-characterized. To begin defining the functions of such poorly characterized proteins, we used mass spectrometry to map…

Read more... Link to related website Email This Item

138
Number of Views